Hyaluronan-Based Scaffolds to Tissue-Engineer Cartilage Implants for Laryngotracheal Reconstruction
نویسندگان
چکیده
منابع مشابه
Tissue Engineered Cartilage Patches for Laryngotracheal Reconstruction
Galway, Ireland Tissue Engineered Cartilage Patches for Laryngotracheal Reconstruction James E. Dennis, David Gilpin, Mark Weidenbecher, Corresponding Author: [email protected] Case Western Reserve University, Cleveland, OH, USA and University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH USA Introduction Currently, the treatment for tracheal stenosis in infants is ...
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OBJECTIVES/HYPOTHESIS To develop an effective rabbit model of in vitro- and in vivo-derived tissue-engineered cartilage for laryngotracheal reconstruction (LTR). STUDY DESIGN 1) Determination of the optimal scaffold 1% hyaluronic acid (HA), 2% HA, and polyglycolic acid (PGA) and in vitro culture time course using a pilot study of 4 by 4-mm in vitro-derived constructs analyzed on a static cult...
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OBJECTIVE To describe the dimensions of cartilage grafts used for successful laryngotracheal reconstruction, with the goal of establishing appropriate sizes for "off-the-shelf" tissue-engineered cartilage grafts. DESIGN A retrospective review of prospectively maintained operative illustrations of a single surgeon's experience. SETTING Two tertiary children's hospitals. PATIENTS A consecut...
متن کاملA tissue-engineering technique for vascularized laryngotracheal reconstruction.
OBJECTIVE To perform laryngotracheal reconstruction (LTR) using a vascularized neotracheal segment. DESIGN A neotracheal segment was created within the sternocleidomastoid muscle. An anterior cricoid split procedure was performed using a pedicled, vascularized neotracheal segment. Results were compared with a control group that underwent anterior cricoid split using standard (avascular) autog...
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ژورنال
عنوان ژورنال: The Laryngoscope
سال: 2007
ISSN: 0023-852X,1531-4995
DOI: 10.1097/mlg.0b013e31811434ae